CLINICAL ASPECTS OF CONFIRMED CASES OF INFLUENCE A (H1N1) PDM09 DURING THE PANDEMIC IN BRAZIL: DATASUS

Fernanda Silva Carvalho; Bruna Almeida Mendes; Luana Kelly Marques  Villafuerte; João Rodrigo Araújo  Silva; Andreza Caroline Oliveira  Cunha

Authors

Fernanda Silva Carvalho Medical Student at Universidade Salvador - Brazil https://orcid.org/0000-0002-0793-6632 http://lattes.cnpq.br/2535625895860970
Bruna Almeida Mendes Medical Student at Universidade Salvador - Brazil https://orcid.org/0000-0002-5705-1701 http://lattes.cnpq.br/2634605319867525
Luana Kelly Marques Villafuerte Medical Student at Universidade Salvador - Brazil https://orcid.org/0000-0001-5704-0853 http://lattes.cnpq.br/2844338888751128
João Rodrigo Araújo Silva Medical Student at Universidade Salvador - Brazil https://orcid.org/0000-0003-1833-8766 http://lattes.cnpq.br/7412613591813470
Andreza Caroline Oliveira Cunha Medical Student at Universidade Salvador - Brazil https://orcid.org/0000-0001-9503-5385 http://lattes.cnpq.br/7136392018218564

Keywords:

Virus H1N1, Severe Acute Respiratory Syndrome, Epidemiology

Abstract

Objective: To describe the clinical aspects of Influenza A (H1N1) pdm09 in Brazil by geographic region, during the pandemic that occurred between 2009 and 2010. Method: This is a descriptive quantitative study. Data were collected from information from the Notifiable Diseases Information System (SINAN), using the Tabnet web tab on the DATASUS website. As inclusion criteria, data recorded during the period 2009 and 2010 were considered; only confirmed cases; and data available for the five Brazilian regions. Results: The region of Brazil with the highest number of confirmed cases of influenza A (H1N1) pdm09 during the pandemic period was the South. The most affected age group varied between regions, but in general, it was predominant in young people and adults. In all locations, the sex with the most confirmed cases was female. The South was also the one with the highest percentage of evolution to SRAG, however, it was the Southeast that had the highest number of SRAG requiring hospital admissions. Despite having the highest number of cases, the South region also had the highest percentage of cure. Conclusion: Brazil suffered great impacts from the influenza A (H1N1) pandemic. Thousands of people were affected. In general, unlike other common flu viruses, the influenza A virus affects younger people and female individuals in all Brazilian regions.

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References

WHO. World Health Organization. Pandemic (H1N1) 2009 - update 82. 2010. Disponível em: https://www.who.int/csr/don/2010_01_08/en/. Acesso em: 01 fev. 2021.

Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team, 2009. Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans. N Engl J Med 2009; 360:2605-2615.

Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Influenza. Influenza. Caderno 1. Guia de Vigilância Epidemiológica. 7a ed. Brasília, (DF): Ministério da Saúde; 2009. p. 1-23 [série A normais e manuais técnicos].

Codeço CT, Cordeiro JS, Lima AWS, Colpo RA, Cruz OG, Coelho FC et al. The epidemic wave of influenza A (H1N1) in Brazil, 2009. Cad. Saúde Pública. 2012;28(7):1325-1336.

Perez-Padilla R, de la Rosa-Zamboni D, Ponce de Leon S, Hernandez M, Quinones-Falconi F, Bautista E, et al. Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico. N Engl J Med2009 [Epub ahead of print].

Pires Neto RJ, Lemos DRQ, Cavalcanti LPG, Ramos Junior AN, Alencar CH, Façanha MC, et al. Pandemic influenza A (H1N1) 2009: Epidemiological analysis of cases in a tropical/semi-arid region of Brazil. Rev Soc Bras Med Trop. 2013;46(2):141-6.

Schout D, Hajjar LA, Galas FRBG, Uip DE, Levin ASS, Caiaffa Filho HH et al. Epidemiology of human infection with the novel virus influenza A (H1H1) in the Hospital das Clínicas, São Paulo, Brazil - june-september 2009. Clinics. 20009; 64(10):1025-30.

Ribeiro AF, Pellini ACG, Kitagawa BY, Marques D, Madalosso G, de Cassia Nogueira Figueira G, et al. (2015) Risk Factors for Death from Influenza A(H1N1)pdm09, State of São Paulo, Brazil, 2009. PLoS ONE 10(3): e0118772. https://doi.org/10.1371/journal.pone.0118772

Oliveira W, Carmo E, Penna G, Kuchenbecker R, Santos H, Araujo W, Malaguti R, Duncan B, Schmidt M; Surveillance Team for the pandemic influenza A(H1N1) 2009 in the Ministry of Health. Pandemic H1N1 influenza in Brazil: Analysis if the first 34,506 notified cases of influenza-like illness with severe acute respiratory infection (SARI). Euro Surveill 2009;14(42):pii=19362.

Moura, Fernanda EA. Influenza in the tropics, Current Opinion in Infectious Diseases. 2010; 23(5):415-420 doi: 10.1097/QCO.0b013e32833cc955

Golynski K S, Marques C M, Avaliação epidemiológica dos casos de influenza a (H1N1) e o impacto da vacinação em indivíduos que residem em Curitiba-PR. Caderno da Escola de Saúde. 2017; 14:32-51.

Kelly HA, Grant KA, Williams S, Fielding J, Smith D. Epidemiological characteristics of pandemic influenza H1N1 2009 and seasonal influenza infection. MJA. 2009;191(3):146-149.

Khandaker G, Dierig A, Rashid H, King C, Heron L, Booy R: Systematic review of clinical and epidemiological features of the pandemic influenza A (H1N1) 2009. Influenza Other Respir Viruses. 2011, 5:148-156.

Punpanich W, Chotpitayasunondh T: A review on the clinical spectrum and natural history of human influenza. Int J Infect Dis. 2012, 16:714-723.

Dhandapani NSPSK. Evaluation of Pregnancy, Younger Age, and Old Age as Independent Risk Factors for Poor Hospitalization Outcomes in Influenza A (H1N1) pdm09 Virus a Decade After the Pandemic. Cureus. 2020;12(11): e11762.

Wang XL, et al. Age and sex differences in rates of influenza-associated hospitalizations in Hong Kong. Am J Epidemiol. 2015;182(4):335–44.

Klein SL, Hodgson A, Robinson DP. Mechanisms of sex disparities in influenza pathogenesis. J Leukoc Biol. 2012;92(1):67–73.

Giefing-Kroll C, et al. How sex and age affect immune responses, susceptibility to infections, and response to vaccination. Aging Cell. 2015;14(3):309–21.

Peretz J, Hall OJ, Klein SL. Sex differences in influenza virus infection, vaccination, and therapies., in Sex and Gender Differences in Infection and Treatments for Infectious Diseases. Springer International Publishing. 2015, 183–210.

Milanesi, Rafaela, Caregnato, Rita Catalina Aquino e Wachholz, Neiva Isabel RaffoPandemia de Influenza A (H1N1): mudança nos hábitos de saúde da população, Cachoeira do Sul, Rio Grande do Sul, Brasil, 2010. Cadernos de Saúde Pública. 2011, 27(4):723-732. Disponível em: <https://doi.org/10.1590/S0102-311X2011000400011>. Epub 09 Maio 2011. ISSN 1678-4464. https://doi.org/10.1590/S0102-311X2011000400011.

Wong K, Luscomb GM, Hawke C. Influenza infections in Australia 2009–2015: is there a combined effect of age and sex on susceptibility to virus subtypes? BMC Infect Dis. 2019, 19(42).

CLINICAL ASPECTS OF CONFIRMED CASES OF INFLUENCE A (H1N1) PDM09 DURING THE PANDEMIC IN BRAZIL: DATASUS

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