LEUKEMIA MORTALITY IN THE STATE OF BAHIA FROM 2008 TO 2018
Keywords:
Mortality, Leukemia, Lymphoid, MyeloidAbstract
Aim: To analyze leukemia mortality in Bahia between 2008 and 2018. Method: Study with aggregated data (ecological time-series), which uses data from the Information and Mortality System of the SUS Computer Department. Differences in proportions of leukemia cases by sociodemographic variables and related to the state's health macro-regions, were assessed by the chi-square or Fisher tests. The data were compiled in Excel® (2007) and the analyzes were performed using the Stata program (v.14). Results: There was an increase in the number of deaths, 2,527 deaths due to leukemia, most of them in the Eastern macro-region (68.2%, p <0.001). Deaths predominated significantly in the elderly population (43.4%, p <0.001), in males (57%, p <0.003) and in individuals without partners (49.2%, p <0.002). There was a predominance of deaths in the brown population (58.8%, p= 0.763) and low education (21.8%, p= 0.074). Higher overall mortality rates (per 100,000 inhabitants) predominated in 2018 (1.91), among males (1.02) and among the elderly (0.95). With regard to types of leukemia, myeloid leukemia obtained higher mortality rates, the highest of which was registered in 2018 (1.05), as well as in males (0.59) and in the elderly (0.59). Conclusion: There was an increase in deaths from leukemias in Bahia, and such deaths were concentrated in the eastern macro-region of the state, which may be associated with an uneven distribution of hematologists concentrated in that region when compared to the rest of the state, in elderly males, of brown color (not statistically significant) and in individuals without partners.
Downloads
References
Goldman L, Schafer AI. Cecil: Medicina. 24a ed. Rio de Janeiro: Saunders-Elsevier; 2012.
Juliusson, G, Hough, R. Leukemia. Progress in Tumor Research. 2016; 43: 87–100. https://doi.org/10.1159/000447076
Rêgo MAV, Fonseca AA. Tendência da Mortalidade por Leucemia em Salvador - Brasil, 1980 a 2012. Revista Brasileira de Cancerologia. 2015; 61(4): 325–34.
Rosa TJ. Paciente acometido por leucemia mieloide aguda com T (6;9): relato de caso. Revista Brasileira de Análises Clínicas. 2018; 50(2): 190–3.
Hamerschlak N. Leukemia: Genetics and prognostic factors. Jornal de Pediatria. 2008; 84(4 SUPPL.): 52–57.
Chiattone, CS. Indicações para início de tratamento na leucemia linfóide crônica. Revista brasileira de hematologia e hemoterapia. 2005;27(4):272-275.
Leal CHS, Wünsch Filho V. Mortalidade por leucemias relacionada à industrialização. Revista de Saúde Pública. 2002; 36(4): 400–408.
Silva-Junior AL, Alves FS, Kerr MWA, Xabregas LA, Gama FM, Rodrigues MGA, et al. Acute lymphoid and myeloid leukemia in a Brazilian Amazon population: Epidemiology and predictors of comorbidity and deaths. PLOS ONE [Internet]. 2019 [acesso em 22 ago 2019]; Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221518
Kipps TJ, Stevenson FK, Wu CJ, Croce CM, Packham G, Wierda WG, et al. Chronic lymphocytic leukaemia. Nature Reviews Disease Primers. 2017; 3, 17008. https://doi.org/10.1038/nrdp.2017.8
Redaelli A, Lee JM, Stephens JM, Pashos CL. Epidemiology and clinical burden of acute myeloid leucemia. Expert Review of Anticancer Therapy. 2003; 3(5): 95–710. https://doi.org/10.1586/14737140.3.5.695
Instituto Brasileiro de Geografia e Estatística [homepage na internet]. Desigualdades Sociais por Cor ou Raça no Brasil. [acesso em 28 nov 2020]. Disponível em: https://www.ibge.gov.br/estatisticas/sociais/populacao/25844-desigualdades-sociais-por-cor-ou-raca.html?=&t=resultados
Oliveira KF, Jannuzzi PM. Motivos para migração no Brasil e retorno ao nordeste: padrões etários, por sexo e origem/destino. São Paulo Em Perspectiva. 2005; 19(4): 134–143. https://doi.org/10.1590/s0102-88392005000400009
Instituto Nacional de Câncer (INCA) [base de dados online]. Onde tratar pelo SUS – Bahia. [acesso em 20 out 2020]. Disponível em: https://www.inca.gov.br/onde-tratar-pelo-sus/bahia
Silva DS, Mattos IE, Teixeira LR. Tendência de Mortalidade por Leucemias e Linfomas em Menores de 20 Anos, Brasil. Revista Brasileira de Cancerologia. 2013; 59(2): 165–173.
Curado MP, Pontes T, Guerra-Yi ME, Cancela MDC. Leukemia mortality trends among children, adolescents, and young adults in Latin America. Revista Panamericana de Salud Publica. Pan American Journal of Public Health. 2011; 29(2): 96–102. https://doi.org/10.1590/S1020-49892011000200004
Bertuccio P, Bosetti C, Malvezzi M, Levi F, Chatenoud L, Negri E, et al. Trends in mortality from leukemia in Europe: An update to 2009 and a projection to 2012. International Journal of Cancer. 2013; 132(2): 427-436. https://doi.org/10.1002/ijc.27624
Santana LR, Almeida MF, Portugal TS, Amaral ALS, Mata-Virgem SF, Vianna MB, et al. Perfil Epidemiológico das Leucemias em Crianças e Adolescentes no Estado da Bahia. Gazeta Médica da Bahia. 2007; 77(Suplemento 1): 51–54.
Deschler B, Lübbert M. Acute myeloid leukemia: Epidemiology and etiology. Wiley InterScience. 2006; 107(9): 2099–2107. https://doi.org/10.1002/cncr.22233
Onciu M. Acute Lymphoblastic Leukemia. Hematology/Oncology Clinics of North America. 2009; 23(4): 655–674. https://doi.org/10.1016/j.hoc.2009.04.009
Ferrara F, Schiffer CA. Acute myeloid leukaemia in adults. The Lancet. 2013; 381(9865): 484–495. https://doi.org/10.1016/S0140-6736(12)61727-9
De Kouchkovsky I, Abdul-Hay M. Acute myeloid leukemia: A comprehensive review and 2016 update. Blood Cancer Journal. 2016; 6(7): e441. https://doi.org/10.1038/bcj.2016.50
Hahn A, Giri S, Yaghmour G, Martin MG. Early mortality in acute myeloid leucemia. Leukemia Research. 2015; 39(5): 505-509. https://doi.org/10.1016/j.leukres.2015.02.003
Saraiva DCA, Santos SS, Monteiro GTR. Tendência de mortalidade por leucemias em crianças e adolescentes nas capitais dos estados brasileiros: 1980-2015. Epidemiologia e Servicos de Saude: Revista Do Sistema Unico de Saude Do Brasil. 2018; 27(3): e2017310. https://doi.org/10.5123/S1679-49742018000300004
Laurenti R, Jorge MHPM, Gotlieb SLD. Perfil epidemiológico da morbi-mortalidade masculina. Ciência & Saúde Coletiva. 2005; 10(1): 35–46.
Oliveira RS, Barbosa AGC, Dias JP, Oliveira EMS, Oliveira JS, Ottoni MAM, et al. Baixa procura dos homens ao serviço de saúde: uma revisão de literatura. EFDeportes.com, Revista Digital [Internet]. 2014 [acesso em 28 nov 2019]; Disponível em: https://www.efdeportes.com/efd188/baixa-procura-dos-homens-ao-servico-de-saude.htm
Terwilliger T, Abdul-Hay M. Acute lymphoblastic leukemia: a comprehensive review and 2017 update. Blood Cancer Journal. 2017; 7(6): e577. https://doi.org/10.1038/bcj.2017.53
Juliusson G, Antunovic P, Derolf A, Lehmann S, Möllgård L, Stockelberg D, et al. Age and acute myeloid leukemia: Real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry. Blood. 2009; 113(18): 4179–4187. https://doi.org/10.1182/blood-2008-07-172007
Ministério da Saúde (BR). Cadastro Nacional de Estabelecimentos de Saúde (CNES) [Internet]. Brasília: Ministério da Saúde; [acesso em 22 nov 2020]. Disponível em: http://www2.datasus.gov.br/DATASUS/index.php?area=0204.
Downloads
Published
How to Cite
Issue
Section
License
Copyright
Submission of originals to Práticas e Cuidado: Revista de Saúde Coletiva (Practices and Care: Journal of Public Health - PC-RESC) implies the transfer of publication rights by the authors. The copyright for manuscripts published in this journal belongs to the authors, with PC-RESC retaining rights over the first publication. The authors may only use the same results in other publications if they explicitly indicate PC-RESC as the original publication medium.
Creative Commons License
Except where otherwise specified, the terms of a Creative Commons Attribution-ShareAlike 4.0 International License apply to the material published in this journal, which permits unrestricted use, distribution, and reproduction in any medium, provided the original publication is correctly cited.
This magazine is licensed under a License 